Covalent/non-covalent recognition strategies for visualized sensing of trace organic amines

Precise, timely and visualized recognition of trace organic amines is of great significance for safeguarding human health, ecological environment, public security, etc., especially crucial for adopting appropriate disposition measures. For this purpose, great efforts have been made to finely design the optical probe structure which is the core of the specific recognition. Here, we proposed the recognition strategies based on either covalent nor non-covalent interactions to achieve the detection towards the targets with primary amine, tryptamine and ethylenediamine [1-2]. These sensing strategies exhibited ppb/nM level sensitivity, specific recognition without disturbance to the potential interferents, as well as rapid optical response within 1 s. Furthermore, by integrating the optical probe with the portable sensing chip, the sensing performances were verified to be capable for detecting the trace analytes in the complicated practical scenarios, providing a valuable reference for designing.