Brevundimonas spp: Emerging global opportunistic pathogens

Non-fermenting Gram-negative bacteria are problematic in clinical locations, being one of the mostprevalent causes of nosocomial infections. Many of these non-fermenting Gram-negative bacteriaare opportunistic pathogens that affect patients that are suffering with underlying medicalconditions and diseases. Brevundimonas spp., in particular Brevundimonas diminuta andBrevundimonas vesicularis, are a genus of non-fermenting Gram-negative bacteria considered ofminor clinical importance. Forty-nine separate instances of infection relating to Brevundimonas sppwere found in the scientific literature along with two pseudo-infections. The majority of theseinstances were infection with Brevundimonas vesicularis (thirty-five cases 71%). The majorcondition associated with Brevundimonas spp infection was bacteraemia with seventeen individualcases/outbreaks (35%). This review identified forty-nine examples of Brevundimonas spp. infectionshave been discussed in the literature. These findings indicate that infection review programs shouldconsider investigation of possible Brevundimonas spp outbreaks if these bacteria are clinicallyisolated in more than one patient.