Cost-effectiveness of population-based screening for colorectal cancer: a comparison of guaiac-based faecal occult blood testing, faecal immunochemical testing and flexible sigmoidoscopy.
journal contribution
posted on 2016-03-01, 12:26 authored by Linda Sharp, Lesley Tilson, Sophie Whyte, Alan O'Ceilleachair, Cathal Dominic Walsh, Cara Usher, Paul Tappenden, James Chilcott, Anthony Staines, Michael Barry, Harry ComberSeveral colorectal cancer-screening tests are available, but it is uncertain which provides the best balance of risks and benefits within a screening programme. We evaluated cost-effectiveness of a population-based screening programme in Ireland based on (i) biennial guaiac-based faecal occult blood testing (gFOBT) at ages 55-74, with reflex faecal immunochemical testing (FIT); (ii) biennial FIT at ages 55-74; and (iii) once-only flexible sigmoidoscopy (FSIG) at age 60.
Funding
Development of a structure identification methodology for nonlinear dynamic systems
National Research Foundation
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British Journal of Cancer;106, pp. 805-816Publisher
Nature Publishing GroupNote
peer-reviewedOther Funding information
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