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Mathematical modelling and simulation of a spray fluidized bed granulator

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posted on 2018-11-06, 14:30 authored by Gurmeet Kaur, Mehakpreet SinghMehakpreet Singh, Jitendra Kumar, Thomas De Beer, Ingmar Nopens
In this present work, a study of the modelling and simulation for a top-sprayed fluidized bed granulator (SFBG) is presented, which is substantially used by the pharmaceutical industry to prepare granules. The idea is to build a number-based mathematical model using the notion of population balances by dividing a top SFBG into two different zones, namely the wet zone and dry zone. To solve a two-compartment model, an existing accurate and efficient finite volume scheme is implemented. In order to validate the compartmental model, a new class of analytical moments is derived corresponding to various combinations of aggregation and breakage kernels. To verify the accuracy of a modified finite volume scheme, the zeroth and first order moments computed using the finite volume scheme are compared with the newly-derived analytical results. Moreover, the stability of the compartmental model and the numerical scheme is tested by varying the size of the wet zone. It is also shown that the relative errors in both order moments increase with the increase in the size of the wet zon

History

Publication

Processes;6, 195

Publisher

MDPI

Note

peer-reviewed

Other Funding information

International Mobility Programme for Academic and Knowledge Transfer, Erasmus Mundus Programme

Language

English

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