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Timely publishing of experiences and sharing of knowledge.

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journal contribution
posted on 2023-02-23, 11:51 authored by Nuala H. O'Connell, Paul Tansey, Suzanne S. Dunne, COLUM DUNNECOLUM DUNNE
Sir, Philip Larkin wrote “man hands on misery to man”. The poet was born in 1922 at the birth of the modern “antibiotic era” and, while he was not referring to infection, the phrase reflects the microbiological phenomenon. Early career doctors, nurses and IPC professionals should feel empowered to report their work and not be over-awed by perceived restrictions or hierarchical clinical and management structures. However, their early career focus is likely to be dominated by ambition for professional success. Controversy, “rocking of boats” and association with incidents of emerging drug resistance may, perhaps, be viewed as best avoided. And such was the case, in 2005, when a 15 year old male cystic fibrosis patient presented with a linezolid-resistant methicillin-sensitive Staphylococcus aureus G2576T mutation secondary to the prolonged use of linezolid by his attending physican in the absence of any specialist advice. Although now superceded by reports in 2006 and 2010 1,2 of similar incidences, at that time we did not publish our learning regarding risks associated with prolonged monotherapy in this setting, ineffective dosing and subsequent bacteriostatic activity.

History

Publication

Journal of Hosptial Infection;97 (3), pp. 315-316

Publisher

Elsevier

Note

peer-reviewed

Rights

This is the author’s version of a work that was accepted for publication in Journal of Hospital Infection. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Hospital Infection, 2017, 97 (3), pp. 315-316, https://doi.org/10.1016/j.jhin.2017.06.028

Language

English

Department or School

  • School of Medicine

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