Many countries are facing a new phase of the pandemic where COVID-19 vaccine roll-out and uptake takes centre stage. Vaccine hesitancy poses a real challenge in pursuit of this goal. Indeed, the World Health Organization (WHO) listed vaccine hesitancy as one of the top 10 threats to global health.1 The need to understand and support uptake of COVID-19 vaccinations is now imperative. To achieve herd immunity, the virus transmission rate, R, and the performance of the vaccine must be taken into account.2
Given higher transmissibility of new variants, and an optimistic estimate of efficacy of .80, reducing the risk of vaccine recipients getting the disease by 80%, herd immunity may require entire populations to be immunised.