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Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants
Mutambudzi, Miriam; Niedzwiedz, Claire L.; Macdonald, Ewan Beaton; Leyland, Alastair; Mair, Frances; Anderson, Jana J.; Celis-Morales, Carlos A.; Cleland, John G.F.; Forbes, John F.; Gill, Jason M.R.; Hastie, Claire E.; Ho, Frederick K.; Jani, Bhautesh; Mackay, Daniel F.; Nicholl, Barbara; O'Donnell, Catherine A.; Sattar, Naveed; Welsh, Paul; Pell, Jill P.; Katikireddi, Srinivasa Vittal; Demou, Evangelia
Date
2020
Abstract
Objectives To investigate severe COVID-19 risk by occupational group. Methods Baseline UK Biobank data (2006–10) for England were linked to SARS-CoV-2 test results from Public Health England (16 March to 26 July 2020). Included participants were employed or self-employed at baseline, alive and aged <65 years in 2020. Poisson regression models were adjusted sequentially for baseline demographic, socioeconomic, work-related, health, and lifestyle-related risk factors to assess risk ratios (RRs) for testing positive in hospital or death due to COVID-19 by three occupational classification schemes (including Standard Occupation Classification (SOC) 2000). Results Of 120 075 participants, 271 had severe COVID-19. Relative to non-essential workers, healthcare workers (RR 7.43, 95% CI 5.52 to 10.00), social and education workers (RR 1.84, 95% CI 1.21 to 2.82) and other essential workers (RR 1.60, 95% CI 1.05 to 2.45) had a higher risk of severe COVID-19. Using more detailed groupings, medical support staff (RR 8.70, 95% CI 4.87 to 15.55), social care (RR 2.46, 95% CI 1.47 to 4.14) and transport workers (RR 2.20, 95% CI 1.21 to 4.00) had the highest risk within the broader groups. Compared with white non-essential workers, non-white non-essential workers had a higher risk (RR 3.27, 95% CI 1.90 to 5.62) and non-white essential workers had the highest risk (RR 8.34, 95% CI 5.17 to 13.47). Using SOC 2000 major groups, associate professional and technical occupations, personal service occupations and plant and machine operatives had a higher risk, compared with managers and senior officials. Conclusions Essential workers have a higher risk of severe COVID-19. These findings underscore the need for national and organisational policies and practices that protect and support workers with an elevated risk of severe COVID-19.
Supervisor
Description
peer-reviewed
Publisher
BMJ Publishing Group
Citation
Occupational and Environmental Medicine;
Collections
Keywords
Funding code
Funding Information
Sustainable Development Goals
External Link
Type
Article
Rights
https://creativecommons.org/licenses/by-nc-sa/1.0/
