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Date
2014
Abstract
Cell-sized polyelectrolyte capsules functionalized with a redox-driven proton pump protein were assembled for the first time. The interaction of polyelectrolyte microcapsules, fabricated by electrostatic layer-by-layer assembly, with cytochrome c oxidase molecules was investigated. We found that the cytochrome c oxidase retained its functionality, that the functionalized microcapsules interacting with cytochrome c oxidase were permeable and that the permeability characteristics of the microcapsule shell depend on the shell components. This work provides a significant input towards the fabrication of an integrated device made of biological components and based on specific biomolecular functions and properties.
Supervisor
Description
peer-reviewed
Publisher
Public Library of Science
Citation
PLoS ONE;9, 11, e112912
Collections
Chemical Sciences
Bernal Institute
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Keywords
polyelectrolyte capsules, biological components
ULRR Identifiers
https://hdl.handle.net/10344/4497
 https://doi.org/10.34961/4685
Funding code
Funding Information
European Research Council (ERC)
Sustainable Development Goals
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