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Past and future burden of inflammatory bowel diseases based on modeling of population-based data
Coward, Stephanie; Clement, Fiona; Benchimol, Eric I.; Bernstein, Charles N.; Avina-Zubieta, Antonio J.; Bitton, Alain; Carroll, Mathew W.; Hazlewood, Glen; Jacobson, Kevan; Jelinski, Susan; Deardon, Rob; Jones, Jennifer L.; Kuenzig, Ellen M.; Leddin, Des; McBrien, Kerry A.; Murthy, Sanjay K.; Nguyen, Geoffrey C.; Otley, Anthony R.; Panaccione, Remo; Rezaie, Ali; Rosenfeld, Greg; Peña-Sánchez, Juan Nicolás; Singh Harminder,; Targownik, Laura E.; Kaplan, Gilaad G.
Date
2019
Abstract
BACKGROUND & AIMS: Inflammatory bowel diseases (IBDs) exist worldwide, with high prevalence in North America. IBD is complex and costly, and its increasing prevalence places a greater stress on health care systems. We aimed to determine the past current, and future prevalences of IBD in Canada. METHODS: We performed a retrospective cohort study using population-based health administrative data from Alberta (2002–2015), British Columbia (1997– 2014), Manitoba (1990–2013), Nova Scotia (1996–2009), Ontario (1999–2014), Quebec (2001–2008), and Saskatchewan (1998–2016). Autoregressive integrated moving average regression was applied, and prevalence, with 95% prediction intervals (PIs), was forecasted to 2030. Average annual percentage change, with 95% confidence intervals, was assessed with log binomial regression. RESULTS: In 2018, the prevalence of IBD in Canada was estimated at 725 per 100,000 (95% PI 716–735) and annual average percent change was estimated at 2.86% (95% confidence interval 2.80%–2.92%). The prevalence in 2030 was forecasted to be 981 per 100,000 (95% PI 963–999): 159 per 100,000 (95% PI 133–185) in children, 1118 per 100,000 (95% PI 1069–1168) in adults, and 1370 per 100,000 (95% PI 1312–1429) in the elderly. In 2018, 267,983 Canadians (95% PI 264,579–271,387) were estimated to be living with IBD, which was forecasted to increase to 402,853 (95% PI 395,466–410,240) by 2030. CONCLUSION: Forecasting prevalence will allow health policy makers to develop policy that is necessary to address the challenges faced by health systems in providing high-quality and cost-effective care.
Supervisor
Description
peer-reviewed
Publisher
Elsevier
Citation
Gastroenterology;156 (5), pp. 1345-1353.e4
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Files
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Leddin_2019_Past.pdf
Adobe PDF, 911.78 KB
Funding code
Funding Information
Digestive Health Strategic Clinical Network, Alberta Health Services, Crohn’s and Colitis Canada, Canadian Association of Gastroenterology
Sustainable Development Goals
External Link
Type
Article
Rights
https://creativecommons.org/licenses/by-nc-sa/1.0/