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Preparation and characterisation of solid state forms of paracetamol-O-glucuronide

Date
2012
Abstract
The synthesis and crystallisation of the pharmaceutically important metabolite, paracetamol-O-glucuronide, is described. Hydrated and anhydrous forms of the target molecule have been characterised by PXRD, DSC and TGA. In addition, a methanol solvate has been analysed, including single crystal analysis, which represents the first structure solution for this system.
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Description
peer-reviewed
Publisher
Elsevier
Citation
Carbohydrate Research;349, pp. 108-112
Collections
Synthesis and Solid State Pharmaceutical Centre
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Hayes_preparation.pdf
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Keywords
paracetamol-O-glucuronide, solvates, hydrates, X-ray diffraction
ULRR Identifiers
https://researchrepository.ul.ie/handle/10344/3110
 https://doi.org/10.34961/1312
Funding code
Funding Information
Science Foundation Ireland (SFI)
Sustainable Development Goals
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Type
Article
Rights
https://creativecommons.org/licenses/by-nc-sa/1.0/
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