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On-site rapid detection of Ethidium Bromide using ultramicroelectrode sensors

Date
2024
Abstract
Ethidium bromide (EtBr) is one of the most fluorescence-based detection of nucleic acids molecule. It also shown to be potentially dangerous due to damage at mitochondrial genome. In the last 10 years, EtBr has also been shown to be electrochemically active. In this work, we show the modification of an ultra-micro electrode sensorand subsequent detection of EtBr from Phosphate buffer ona nanomolar level (LoD of 12 nM). The sensor can detect concentrations with a higher sensitivity and reliability than the classic UV lamp in a practical manner. This novel sensor may offer a potential solution to test for and reduce potentials risks associated with both job related risk and unwanted environmental release of EtBr.
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Description
Publisher
University of Limerick
Citation
20th Sensors and Their Applications Conference, 2024, Paper No: 66
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20th Sensors & Their Applications Conference
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Paper_66.pdf
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Keywords
ethidium bromide, chemosensor, electrochemical detection, electrochemestry, Biological sciences
ULRR Identifiers
https://doi.org/10.34961/researchrepository-ul.29302235
 https://researchrepository.ul.ie/handle/10344/14829
Funding code
Funding Information
Sustainable Development Goals
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Type
Meetings and Proceedings
Rights
https://creativecommons.org/licenses/by-nc-sa/4.0/
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