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Adipocyte-epithelial interactions and crohn's disease - an emerging drug target
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Date
2017
Abstract
Crohn's disease is hallmarked by mesenteric abnormalities including thickening, shortening and extension ofmesenteric fat over the intestinal surface (“fat wrapping” or “creeping fat”) (Coffey et al., 2016; Peyrin-Biroulet et al., 2007; Sheehan et al., 1992; Crohn et al., 1932). Mesenteric and submucosal mesenchymal abnormalities overlap in histological appearance and both inflammatory fronts meet to generate transmural inflammation (Coffey and O'leary, 2016).
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Description
peer-reviewed
Publisher
Elsevier
Citation
EBioMedicine;23, pp. 193-94