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Prevalence of postoperative neurocognitive disorders in older non-cardiac surgical patients: A systematic review and meta-analysis

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Abstract
The growing number of older persons undergoing surgery are at a higher risk of neurocognitive disorder due to multimorbidity and age-related changes. Previous reviews estimated postoperative neurocognitive disorder or cognitive dysfunction (POCD) prevalence without accounting for the sample size or study quality. The prevalence of POCD in this population requires further investigation. This systematic review and meta-analysis applies systematic weighting to estimate the pooled prevalence of POCD in older non-cardiac surgical patients.
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Description
Publisher
Elsevier
Citation
Journal of Clinical Anesthesia 103, 111830
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School of Medicine
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Huang_2025_Prevalence.pdf
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Keywords
postoperative cognitive dysfunction (POCD), postoperative neurocognitive disorder, perioperative neurocognitive disorders, older adults, non-cardiac surgeries, systematic review and meta-analysis, Health sciences
ULRR Identifiers
https://doi.org/10.34961/researchrepository-ul.28804421
 https://hdl.handle.net/10344/15205
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Funding Information
Canadian Institutes of Health Research (CIHR) Canada Graduate Scholarships Doctoral Award (funding reference number: FBD-195197), the Ontario Ministry of Health Innovation Grant, ResMed Foundation, and University Health Network Foundation.
Sustainable Development Goals
(3) Good Health and Well-Being
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