Difficulties arising in reimbursement recommendations on new medicines due to inadequate reporting of population adjustment indirect comparison methods
posted on 2021-02-26, 12:00authored byEileen M. Holmes, Joe Leahy, Arthur White, Peter T. Donnan, Felicity Lamrock
Indirect treatment comparisons are useful to estimate relative treatment effects when head‐to‐head studies are not conducted. Statisticians at the National Centre for Pharmacoeconomics Ireland (NCPE) and Scottish Medicines Consortium (SMC) assess the clinical and cost‐effectiveness of new medicines as part of multidisciplinary teams. We describe some shared observations on areas where reporting of population‐adjustment indirect comparison methods is causing uncertainty in our recommendations to decision‐making committees when assessing reimbursement of medicines.
History
Publication
Research Synthesis Methods;10 (4), pp.. 615-617
Publisher
Taylor and Francis
Note
peer-reviewed
Rights
This is an Author's Accepted Manuscript of an article whose final and definitive form, the Version of Record, has been published in Research Synthesis Methods 2019 copyright Taylor & Francis, available online at: https://doi.org/10.1002/jrsm.1368